Cutaneous amyloid elastosis revealing multiple myeloma with systemic amyloidosis.

Myeloma-associated Systemic Amyloidosis with an Extensive Cutaneous Involvement

Primary systemic amyloidosis (PSA) mostly occurs in the setting of plasma cell dyscrasias.[1] It is difficult to diagnose as it usually presents with nonspecific symptoms.[2] Mucocutaneous manifestations occur in 29%–40% of cases and provide important diagnostic clues.[3] We report an atypical case where an unusually extensive cutaneous involvement provided the first sign of a widespread multio...

Bullous amyloidosis is a rare cutaneous manifestation of systemic AL amyloidosis that may be associated with multiple myeloma or occult plasma cell dyscrasia

© 2010 The Authors. doi: 10.2340/00015555-0871 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Bullous amyloidosis is a rare cutaneous manifestation of systemic AL amyloidosis that may be associated with multiple myeloma or occult plasma cell dyscrasia (1–3); only approximately 30 cases have been reported until now (4, 5), although its incidence may be higher than is gener...

Gastrointestinal Tract Amyloidosis Presenting With Pneumatosis Intestinalis

Pneumatosis intestinalis is a radiographic finding of gas pockets within the bowel wall. It can be associated with a range of diagnoses, but the most life-threatening causes are mesenteric ischemia, bowel necrosis, and bowel obstruction. Here we present the case of a patient with multiple myeloma who had pneumatosis intestinalis due to gastrointestinal amyloidosis, which is a rare manifestation...

Multiple Myeloma with HBs Antigenemia Presented with Hoarseness and Systemic Amyloidosis

[Localized primary cutaneous nodular amyloidosis in a patient with paraproteinemia].

The term primary cutaneous amyloidosis (PCA) refers to a group of diseases caused by the extracellular deposition of amyloid in the skin without the involvement of other organs. PCA has been divided into the following types: macular, lichen and nodular. The first 2 types are characterized by the deposition in the papillary dermis of amyloid derived from the degeneration of keratin filaments. Pr...